Solid microspheres from FDA approved Bioglasses (silicates)
Successfully manufactured solid (non-porous) glass microspheres from the 45S5 and S53P4 glasses.
Islam MT, Nuzulia NA, Macri-Pellizzeri L, Nigar F, Sari YW, Ahmed I. Evolution of silicate bioglass particles as porous microspheres with a view towards orthobiologics. J Biomater Appl. 2022 Mar;36(8):1427-1443. doi: 10.1177/08853282211059294.
Silicate Bioglass (45S5)
FDA Approved - Bone Graft substitute Market available materials
Silicate Bioglass (S53P4)
• The composition of BonAlive® bioactive glass S53P4 by weight is:
• 53% Silicon (SiO2), 23% Sodium (Na2O), 20% Calcium (CaO), 4% Phosphorus (P2O5)
• Irregular shaped particles
• Lindfors NC (2011) Clinical Experience on Bioactive Glass S53P4 in Reconstructive Surgery in the Upper Extremity
Showing Bone Remodelling, Vascularization, Cartilage Repair and Antibacterial Properties of S53P4. J Biotechnol
Biomaterial 1:111. doi:10.4172/2155-952X.100011
Bio-Silicate Glasses